Metastatic Castration-Resistant Prostate Cancer
Metastatic castration-resistant prostate cancer (mCRPC) is an advanced form of prostate cancer that continues to progress despite androgen deprivation therapy (ADT). A subset of mCRPC…
Malignant Neoplasm of Ovary Associated
Malignant neoplasms of the ovary are among the most fatal gynecologic malignancies, and mutations in the BRCA1 and BRCA2 genes significantly increase the risk. Women…
Germline BRCA-Mutated, HER2-Negative Breast Cancer
Germline BRCA mutations are genetic alterations in the BRCA1 or BRCA2 genes, inherited from parents. These mutations significantly increase the risk of developing breast cancer,…
Germline BRCA-Mutated Metastatic Pancreatic Adenocarcinoma
Germline BRCA-mutated metastatic pancreatic adenocarcinoma (gBRCA-mPA) is a rare yet significant subtype of pancreatic cancer associated with inherited BRCA1 and BRCA2 gene mutations. Understanding its…
Epithelial ovarian cancer with brca mutation
Epithelial ovarian cancer (EOC) is one of the most lethal gynecologic malignancies. Mutations in the BRCA1 and BRCA2 genes significantly increase the risk of developing…