TNF Receptor-Associated Periodic Fever Syndrome (TRAPS)
TNF receptor-associated periodic fever syndrome (TRAPS) is a rare hereditary autoinflammatory disorder characterized by recurrent episodes of fever, systemic inflammation, and various other symptoms affecting the skin, eyes, muscles, and joints. It is associated with mutations in the TNFRSF1A gene, which encodes the tumor necrosis factor receptor 1 (TNFR1)—a critical component of the immune system’s