Severe Recalcitrant Nodular Acne
Severe recalcitrant nodular acne is the most advanced and persistent form of acne vulgaris, characterized by deep, inflamed, and painful nodules that are resistant to…
Severe Psychosis
Severe psychosis is a profound mental health condition characterized by a significant detachment from reality, often accompanied by hallucinations, delusions, and disorganized thought processes. It…
Severe Pruritus
Severe pruritus refers to an intense, persistent itching sensation that significantly disrupts a patient's quality of life. Unlike occasional or mild itching, this condition is…
Severe Pre-Eclampsia
Severe pre-eclampsia is a life-threatening hypertensive disorder of pregnancy, typically emerging after 20 weeks of gestation. Characterized by sustained high blood pressure (≥160/110 mmHg) and…
Severe Persistent Asthma
Severe persistent asthma is the most critical classification within the asthma spectrum, marked by chronic, unrelenting symptoms that are poorly controlled despite high-dose medications. These…
Severe Pain with Opioid Tolerance
Patients who develop opioid tolerance often experience diminished analgesic effects despite increasing dosages, leading to refractory severe pain. This condition presents one of the most…
Severe Pain
Severe pain represents an intense, often debilitating sensory and emotional experience associated with actual or potential tissue damage. It may arise suddenly as acute pain…
Severe Ocular Inflammation
Severe ocular inflammation refers to intense inflammatory responses within the eye's structures, including the uvea, sclera, retina, and optic nerve. Left untreated, this condition can…
Severe Myoclonic Epilepsy in Infancy
Severe Myoclonic Epilepsy in Infancy (SMEI), also known as Dravet Syndrome, is a rare but catastrophic epileptic encephalopathy beginning in the first year of life.…
Severe Malaria
Severe malaria is a life-threatening condition caused primarily by Plasmodium falciparum infection. It arises when parasitemia is extensive or when vital organ dysfunction occurs. Unlike…