Proopiomelanocortin (POMC) deficiency is a rare form of monogenic obesity characterized by early-onset severe obesity, adrenal insufficiency, and red hair pigmentation in most cases. The…
Leptin receptor (LEPR) deficiency is a rare genetic disorder leading to severe, early-onset obesity caused by disruptions in the body's energy regulation system. As a…
Bardet-Biedl Syndrome (BBS) is a rare autosomal recessive ciliopathy characterized by multisystemic manifestations, among which obesity is a hallmark. Unlike primary obesity, obesity associated with…