Diseases

Pseudomonas aeruginosa biliary tract infection represents a severe and potentially life-threatening condition involving the invasion of the biliary system by the opportunistic gram-negative bacterium P. aeruginosa. These infections, often hospital-acquired, require prompt diagnosis and targeted antimicrobial therapy due to the pathogen’s intrinsic resistance mechanisms and the vulnerability of the affected patients. Understanding the Pathogen: Pseudomonas

Pseudogout, medically known as calcium pyrophosphate deposition disease (CPPD), is an inflammatory joint condition characterized by the deposition of calcium pyrophosphate dihydrate crystals in the joints. These crystal deposits lead to episodes of joint pain and swelling, often mimicking gout, but with distinct pathophysiology and clinical implications. What Is Pseudogout? Understanding Calcium Pyrophosphate Deposition Disease

Pruritus, commonly referred to as itching, is a highly prevalent and distressing symptom in patients with end-stage renal disease (ESRD) undergoing hemodialysis. Known as uremic pruritus, this condition is underrecognized despite its significant impact on quality of life, sleep, and morbidity. A systematic, pathophysiologically informed approach to diagnosis and treatment is essential in managing pruritus

Providencia septicemia, a rare but serious bloodstream infection, is increasingly reported among hospitalized patients, particularly those with indwelling devices or immunocompromised status. This condition, most commonly caused by Providencia stuartii and Providencia rettgeri, presents a growing clinical concern due to its inherent multidrug resistance and high morbidity in vulnerable populations. In this article, we examine

Proteus pneumonia is an infrequent but clinically significant infection of the lower respiratory tract caused by Proteus species, predominantly Proteus mirabilis. Typically affecting immunocompromised individuals or those with prolonged hospital stays, this gram-negative pneumonia is associated with high morbidity and requires early identification and targeted treatment for optimal outcomes. Microbiological Insights into Proteus Species Characteristics

Pelvic inflammatory disease (PID) is a serious reproductive health concern characterized by infection of the female upper genital tract. While Neisseria gonorrhoeae and Chlamydia trachomatis are common etiological agents, Proteus mirabilis, a gram-negative facultative anaerobe, has been increasingly recognized in polymicrobial PID, particularly among individuals with underlying urogenital infections. This article provides a comprehensive overview

Proteus mirabilis is a gram-negative, facultatively anaerobic bacillus belonging to the Enterobacteriaceae family. Recognized for its urease production and robust motility, it is a prominent cause of complicated urinary tract infections (UTIs), particularly in catheterized individuals, patients with urinary tract abnormalities, or recurrent infections. This article provides a comprehensive, evidence-based analysis of the pathogenesis, clinical

Proteus mirabilis, a gram-negative facultative anaerobe, is an opportunistic pathogen increasingly associated with osteomyelitis, particularly in immunocompromised patients and those with chronic wounds, trauma, or prosthetic implants. This article presents a detailed, evidence-based exploration of the pathogenesis, diagnosis, treatment, and surgical interventions relevant to Proteus mirabilis osteomyelitis. Microbiological Profile and Pathogenesis of Proteus mirabilis in

Proteus meningitis is a rare but severe form of bacterial meningitis predominantly caused by Proteus mirabilis, a gram-negative bacillus. This condition is associated with high morbidity and mortality, particularly among neonates, immunocompromised individuals, and patients with neurosurgical interventions. Prompt recognition and appropriate antimicrobial therapy are crucial for favorable outcomes.​ Etiology and Pathogenesis Proteus mirabilis is

Proteus joint infections, though relatively uncommon compared to other causative agents, represent a serious clinical challenge, particularly in cases of prosthetic joint implantation or compromised host immunity. Proteus mirabilis, a motile, urease-producing gram-negative bacillus, is the predominant species implicated. Its capacity for biofilm formation and multidrug resistance necessitates a robust, evidence-based approach to diagnosis and