Systemic lupus erythematosus (SLE) is a complex and chronic autoimmune disorder that can affect multiple organ systems, including the skin, kidneys, joints, heart, and lungs.…
Systemic dermatomyositis is a chronic, idiopathic inflammatory myopathy characterized by distinctive cutaneous manifestations and progressive symmetrical proximal muscle weakness. As a multisystem autoimmune disease, it…
Systemic cryptococcosis, primarily caused by Cryptococcus neoformans and Cryptococcus gattii, represents a severe fungal infection that often manifests as cryptococcal meningoencephalitis. This life-threatening condition frequently…
Systemic candidiasis, also referred to as invasive candidiasis, is a life-threatening fungal infection primarily caused by Candida species, most commonly Candida albicans, C. glabrata, C.…
Systemic anaplastic large cell lymphoma (sALCL) is a rare but aggressive subtype of non-Hodgkin lymphoma (NHL), classified under mature peripheral T-cell lymphomas. It is characterized…
Syphilis is a chronic, systemic sexually transmitted infection caused by the spirochete bacterium Treponema pallidum. The disease progresses in distinct clinical stages, each with its…
Synovial sarcoma is a rare and aggressive soft tissue malignancy that arises from mesenchymal cells. Despite its name, it does not originate from synovial tissue…
Streptococcal endocarditis, a subset of infective endocarditis (IE), predominantly affects native heart valves and is most commonly caused by viridans group streptococci (VGS), Streptococcus bovis,…
Staphylococcal septicemia, caused predominantly by Staphylococcus aureus, is a life-threatening bloodstream infection marked by rapid progression to sepsis, organ dysfunction, and high mortality rates. The…
Staphylococcal osteomyelitis, particularly that caused by Staphylococcus aureus, remains a significant therapeutic challenge due to its ability to invade bone tissue, form biofilms, and persist…