Vascular Access Thrombosis

Vascular access thrombosis is a significant complication in patients undergoing hemodialysis. It involves the formation of a blood clot within the vascular access site, such as an arteriovenous (AV) fistula, AV graft, or central venous catheter. The condition is a leading cause of vascular access failure, contributing to increased morbidity, hospitalization rates, and health care

Variegate Porphyria

Variegate porphyria (VP) is a rare genetic disorder that affects heme biosynthesis—the process responsible for producing heme, an essential component of hemoglobin. Caused by mutations in the PPOX gene, this autosomal dominant condition leads to the accumulation of porphyrin precursors in the body, triggering both neurovisceral and cutaneous symptoms. VP is one of the hepatic

Varicose Veins

Varicose veins are enlarged, twisted veins that typically appear on the legs and feet due to weakened or damaged vein valves. These dysfunctional valves lead to chronic venous insufficiency, where blood pools in the veins rather than returning efficiently to the heart. While often perceived as a cosmetic issue, varicose veins may cause discomfort, pain,

Varicella Vaccination

Varicella, commonly known as chickenpox, is a highly contagious disease caused by the varicella-zoster virus (VZV). Though often self-limiting in children, varicella can result in severe complications such as bacterial superinfections, pneumonia, and encephalitis, particularly in immunocompromised individuals and adults. The introduction of the varicella vaccination has dramatically reduced incidence, morbidity, and mortality associated with

Vancomycin-Resistant Enterococcus faecium Infection

Vancomycin-resistant Enterococcus faecium (VRE) is an opportunistic, multidrug-resistant pathogen and a major cause of nosocomial infections. It poses a significant challenge in healthcare settings due to its ability to colonize, persist in the environment, and resist first-line antimicrobial agents. Infections range from asymptomatic colonization to life-threatening conditions such as bacteremia, urinary tract infections, endocarditis, and

Vancomycin-Resistant Enterococcus faecium Bacteremia

Vancomycin-resistant Enterococcus faecium (VRE) represents a formidable nosocomial pathogen, responsible for a growing number of bloodstream infections worldwide. These infections predominantly affect immunocompromised patients, individuals with prolonged hospital stays, and those exposed to broad-spectrum antibiotic therapy. Due to limited therapeutic options, high transmission potential, and increased morbidity and mortality, VRE bacteremia has emerged as a

Vaginal Hysterectomy Infection Prevention

Vaginal hysterectomy is a minimally invasive procedure preferred for treating benign gynecological conditions such as fibroids, uterine prolapse, and abnormal bleeding. Despite its advantages—reduced recovery time, minimal scarring, and shorter hospital stays—this surgery carries a risk of post-operative infections, including surgical site infections (SSIs), vaginal cuff cellulitis, and pelvic abscesses. Implementing a thorough, protocol-driven infection

Vaginal Cuff Surgery Post-Op Peptococcus Infection

Vaginal cuff surgery is performed during total hysterectomy procedures to close the top of the vaginal canal after the removal of the uterus and cervix. Although typically uneventful, this surgical site is susceptible to post-operative infections, especially by anaerobic organisms such as Peptococcus. These infections can complicate recovery, delay wound healing, and, if untreated, lead

Vaginal Cuff Surgery Post-Op Infection

Vaginal cuff surgery is a critical component of a total hysterectomy, wherein the upper portion of the vagina is sutured following the removal of the uterus and cervix. This area, known as the vaginal cuff, is vulnerable to post-operative complications, particularly infections, which may arise due to microbial contamination, improper healing, or tissue necrosis. Vigilant

Vaginal Cuff Surgery Post-Op Clostridium Infection

Vaginal cuff surgery, typically following a total hysterectomy, involves suturing the top portion of the vaginal canal after removal of the uterus. While usually successful, a major postoperative risk includes infectious complications—among which Clostridium species, particularly Clostridium difficile and Clostridium perfringens, present a rare but dangerous threat. These gram-positive, spore-forming anaerobes can lead to fulminant