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Severe adrenal insufficiency is a potentially life-threatening endocrine disorder resulting from inadequate production of cortisol and, in some cases, aldosterone by the adrenal glands. Cortisol plays a critical role in maintaining blood pressure, glucose metabolism, and immune regulation. Failure to promptly diagnose and treat this condition, especially during acute stress, can result in adrenal crisis—a

Serum sickness is a type III hypersensitivity reaction characterized by the formation of immune complexes following exposure to foreign proteins or antigens, typically introduced through certain medications, antitoxins, or infections. These immune complexes deposit in tissues, triggering systemic inflammation and vascular injury. Though historically associated with animal-derived antiserum therapies, modern cases are more often linked

Serratia urinary tract infections (UTIs) are uncommon but clinically significant infections caused primarily by Serratia marcescens, a gram-negative, facultative anaerobic bacillus. Most cases occur in healthcare settings and are often associated with indwelling urinary catheters or instrumentation. Due to Serratia’s intrinsic resistance to multiple antibiotics and its potential to cause persistent and recurrent infections, prompt

Serratia pneumonia is an uncommon but clinically significant pulmonary infection caused predominantly by Serratia marcescens, a facultative gram-negative bacillus. Although rare in healthy individuals, it poses a considerable threat in hospitalized or immunocompromised patients due to its inherent resistance to multiple antibiotics and association with ventilator-associated pneumonia (VAP) and healthcare-associated pneumonia (HCAP). Pathophysiology and Transmission

Serratia meningitis is a rare but severe form of bacterial meningitis predominantly caused by Serratia marcescens, a gram-negative bacillus. This opportunistic pathogen is more frequently associated with nosocomial infections, particularly in immunocompromised individuals, neonates, and patients with indwelling medical devices. Meningitis caused by this organism often carries a poor prognosis due to diagnostic delays and

Serratia marcescens, a gram-negative bacillus from the Enterobacteriaceae family, is a rare but serious cause of septic arthritis, especially in immunocompromised hosts and patients with prosthetic joints. While more commonly implicated in urinary and respiratory infections, its ability to colonize orthopedic hardware and synovial tissue makes it a formidable pathogen in joint infections. Complications such

Serratia marcescens, a gram-negative, opportunistic bacillus from the Enterobacteriaceae family, is an emerging pathogen in complicated urinary tract infections (UTIs). These infections often arise in healthcare settings, especially in patients with urinary catheters, structural urologic abnormalities, or immunosuppressive conditions. Due to intrinsic and acquired resistance mechanisms, managing a Serratia complicated UTI requires a precise and

Serratia bronchitis is a respiratory tract infection caused by the Serratia marcescens bacterium, a gram-negative, facultative anaerobe commonly associated with healthcare environments. Though typically an opportunistic pathogen, it can cause serious bronchial infections, particularly in immunocompromised patients, those with underlying lung disease, or individuals with indwelling respiratory devices. Given its potential resistance to multiple antibiotics,