Health conditions and diseases starting with P. Explore reliable details on symptoms, causes, and treatments to protect your well-being.
Progressive fibrosing interstitial lung disease (PF-ILD) is a group of pulmonary disorders characterized by the progressive scarring of lung tissue. This condition involves the interstitium, which is the tissue and space surrounding the air sacs (alveoli) of the lungs. The disease often leads to a gradual decline in lung function, making early detection and timely
Progressive diffuse large B-cell lymphoma (DLBCL) is an aggressive form of non-Hodgkin lymphoma (NHL), which is characterized by the rapid growth of abnormal B-cells in the lymphatic system. DLBCL can arise in lymph nodes, spleen, bone marrow, or extranodal tissues such as the gastrointestinal tract, skin, and central nervous system. The disease progresses rapidly, which
Progressive chronic lymphocytic leukemia (CLL) is a type of cancer that affects the blood and bone marrow, leading to the abnormal growth of white blood cells known as lymphocytes. As CLL progresses, these cells multiply uncontrollably and impair the body’s immune system. This article will explore the key aspects of progressive chronic lymphocytic leukemia, including
Proctitis is an inflammatory condition of the rectum, characterized by swelling and irritation. It can be caused by a variety of factors, including infections, inflammatory bowel disease (IBD), and radiation therapy. The condition is often painful, and its symptoms can significantly impact the quality of life of those affected. In this article, we will explore
Processing-deficient progeroid laminopathy linked to a heterozygous LMNA mutation is a rare genetic disorder marked by premature aging features and multisystem involvement. The disorder arises from defects in the post-translational processing of lamin A, a key structural protein of the nuclear envelope encoded by the LMNA gene. The pathological consequence is a toxic buildup of
Primary Progressive Multiple Sclerosis (PPMS) is a distinct subtype of multiple sclerosis characterized by a steady neurological decline from onset without clear relapses or remissions. Unlike relapsing-remitting MS, PPMS represents approximately 10–15% of all MS cases and typically presents later in life, often around the age of 40. The progressive nature of PPMS stems from
Primary prevention of coronary heart disease (CHD) involves proactively addressing modifiable risk factors before the onset of clinical symptoms. This preventative approach significantly reduces the incidence of myocardial infarction, sudden cardiac death, and other cardiovascular complications. We emphasize the implementation of evidence-based strategies through lifestyle modification, pharmacologic interventions, and targeted screenings. Epidemiology and Public Health
Primary ovarian failure (POF), also known as primary ovarian insufficiency (POI), is a clinical syndrome characterized by the loss of normal ovarian function before the age of 40. It leads to infertility, hypoestrogenism, and elevated gonadotropin levels. While the condition resembles natural menopause, it occurs significantly earlier and may present intermittently rather than being a
Primary mediastinal large B-cell lymphoma (PMBCL) is an aggressive subtype of diffuse large B-cell lymphoma (DLBCL), distinguished by its origin in the thymic (anterior) mediastinum and unique clinical and biological features. Though it accounts for approximately 2–4% of all non-Hodgkin lymphomas, it is a critical entity due to its distinct pathology, treatment requirements, and demographic
Primary malignant neoplasms of the gastrointestinal (GI) tract refer to cancers originating within the various sections of the GI system, which includes the esophagus, stomach, small intestine, colon, rectum, liver, and pancreas. These malignancies represent a major global health burden and are among the leading causes of cancer-related mortality worldwide. Early detection and prompt intervention