Health conditions and diseases starting with P. Explore reliable details on symptoms, causes, and treatments to protect your well-being.
Protein C deficiency is a rare but significant hereditary or acquired disorder of the coagulation system, characterized by an increased risk of thromboembolic events due to impaired natural anticoagulation. As a vital component of the protein C pathway, a deficiency in this protein disrupts the body’s ability to regulate blood clot formation, posing a substantial
Prosthetic heart valve endocarditis (PVE) remains a severe and potentially life-threatening condition in cardiology and cardiac surgery. Despite advancements in valve technology and antibiotic prophylaxis, it presents with high morbidity and mortality. We examine the etiology, pathophysiology, diagnosis, and current therapeutic strategies surrounding PVE, integrating current best practices and innovations. Overview of Prosthetic Valve Endocarditis
Prosthetic joint infections (PJIs) represent a significant challenge in orthopedic surgery, compromising patient outcomes and increasing healthcare costs. Preventing infections following prosthetic arthroplasty requires a multifaceted approach involving meticulous surgical technique, optimized patient selection, and evidence-based perioperative protocols. Understanding Prosthetic Joint Infections: Epidemiology and Impact PJIs occur in approximately 1–2% of primary joint replacements and
Prostatic carcinoma, commonly known as prostate cancer, remains a leading cause of cancer-related morbidity and mortality among men worldwide. Early detection, accurate staging, and evolving treatment modalities have significantly improved clinical outcomes. This article provides a comprehensive analysis of the disease’s pathology, clinical presentation, diagnostic strategies, therapeutic options, and emerging trends in management. Understanding Prostatic
Prostate cancer remains one of the most prevalent malignancies among men globally. Accurate detection of metastatic spread is essential for determining prognosis, guiding therapeutic choices, and evaluating treatment response. Imaging plays a pivotal role in the staging and surveillance of prostatic cancer, particularly in identifying distant metastases. In this comprehensive overview, we examine the latest
Propionic acidemia (PA) is a rare but serious inherited metabolic disorder belonging to the group of organic acidemias. It results from a deficiency in the enzyme propionyl-CoA carboxylase (PCC), which is essential for breaking down certain proteins and fats. Without this enzyme, toxic levels of propionic acid accumulate in the body, leading to severe metabolic
Dextran solutions, particularly Dextran 40 and Dextran 70, are commonly used as volume expanders in medical practice, especially in emergency and critical care settings. These polysaccharide solutions are frequently administered to treat hypovolemia, shock, and blood loss, as they are effective in increasing plasma volume. However, despite their widespread use, they can occasionally trigger adverse
Tympanostomy tube insertion, commonly known as ear tube surgery, is a frequently performed procedure designed to treat recurrent ear infections, chronic otitis media with effusion, or other middle ear disorders. Though this surgery can provide significant relief for patients, particularly children, it comes with a set of potential complications. Prophylaxis, or preventive measures, plays a
Progressive vaccinia (PV) is a rare and severe complication of the smallpox vaccination, primarily affecting individuals with weakened immune systems. The disease is caused by the vaccinia virus, a virus used in the smallpox vaccine. While smallpox eradication has been successful, the risk of progressive vaccinia still poses a threat to those with compromised immunity.
Progressive keratoconus is a complex and degenerative eye condition that affects the cornea, leading to visual impairment due to corneal thinning and distortion. This condition gradually worsens over time, causing the cornea to become more conical in shape, which disrupts the normal focusing ability of the eye. The condition can significantly affect an individual’s quality