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Cytomegalovirus (CMV) is the most common opportunistic infection following cardiac transplantation. It is associated with direct effects such as CMV syndrome and tissue-invasive disease, as well as indirect consequences including graft rejection, allograft vasculopathy, and increased mortality. The prevention of CMV disease after cardiac transplantation is essential to ensure both graft and patient survival. A

Cisplatin remains a cornerstone chemotherapeutic agent for treating various solid tumors, including testicular, ovarian, head and neck, and lung cancers. However, its clinical efficacy is compromised by dose-limiting toxicities, notably ototoxicity, which manifests as irreversible, bilateral sensorineural hearing loss. The incidence of cisplatin-induced ototoxicity (CIO) varies from 20% to over 60%, with children and the

Chemotherapy-induced neurotoxicity, particularly peripheral neuropathy, is a frequent and often dose-limiting complication of cancer treatment. This form of neurotoxicity primarily affects sensory nerves and is commonly associated with agents such as platinum compounds, taxanes, vinca alkaloids, and proteasome inhibitors. Preventing neurotoxicity not only preserves functional integrity but also ensures uninterrupted and effective oncologic treatment. Understanding

Chemotherapy-induced mucositis is a debilitating inflammatory condition of the mucosal lining of the gastrointestinal tract, most commonly manifesting in the oral cavity. It significantly compromises nutritional intake, causes intense pain, increases infection risk, and often necessitates chemotherapy dose reductions or delays. Given its profound impact on patient outcomes and quality of life, implementing effective preventive

Chemotherapy-induced hemorrhagic cystitis (HC) is a serious urological complication predominantly associated with the use of alkylating agents such as cyclophosphamide and ifosfamide. It manifests as bladder mucosal bleeding, dysuria, hematuria, and potential long-term bladder dysfunction. Prevention is imperative to avoid treatment delays, hospitalizations, or severe morbidity. This comprehensive clinical guide outlines robust, evidence-backed strategies for

Cerebrovascular accidents (CVAs), commonly known as strokes, represent a leading cause of mortality and long-term disability worldwide. Effective prevention strategies are essential to reduce incidence and burden. This article presents a structured, evidence-based approach to preventing both ischemic and hemorrhagic strokes by addressing modifiable risk factors, implementing medical interventions, and promoting public health education. Understanding

Cerebral thrombosis, a major cause of ischemic stroke, arises from the formation of a blood clot within the cerebral arteries, obstructing blood flow to the brain. Prevention of cerebral thrombosis is critical in reducing the global burden of stroke and its devastating consequences. We present an exhaustive clinical and preventive approach tailored to minimize thrombotic

Cardiac transplant rejection remains a critical concern in post-operative care and long-term prognosis for heart transplant recipients. Timely prevention and control of immune-mediated graft injury are essential for preserving cardiac function, ensuring graft longevity, and improving patient survival. We present an in-depth exploration of preventive protocols, therapeutic advancements, and clinical monitoring essential to managing and

Chemotherapy-induced thrombocytopenia (CIT) presents a significant clinical challenge in oncology, often necessitating dose reductions or delays in treatment. Proactive prevention strategies are essential to minimize patient risk, maintain therapeutic efficacy, and optimize clinical outcomes. This article presents an in-depth overview of the mechanisms, risk factors, and evidence-based interventions for preventing CIT. Understanding Chemotherapy-Induced Thrombocytopenia Pathophysiology