Myelofibrosis
Myelofibrosis (MF) is a rare but serious myeloproliferative neoplasm (MPN) characterized by abnormal fibrotic tissue accumulation in the bone marrow. This disrupts normal blood cell production, leading to anemia, an enlarged spleen (splenomegaly), and a high risk of transformation into acute myeloid leukemia (AML). Advances in targeted therapies have improved patient outcomes, yet myelofibrosis remains