Latent Late Syphilis

Syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum, progresses through distinct stages: primary, secondary, latent, and tertiary. The latent stage, particularly its late phase, is characterized by the absence of symptoms, making it a silent yet potentially harmful phase if left untreated. This article provides an in-depth examination of latent late syphilis,

Latent Early Syphilis

Syphilis, a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum, progresses through distinct stages: primary, secondary, latent, and tertiary. The latent stage is particularly insidious, as it presents no visible symptoms yet harbors the potential for severe health complications if left untreated. This article delves into the nuances of latent early syphilis, encompassing

​Latent bejel

Latent bejel, also known as endemic syphilis, is a chronic, non-venereal treponemal infection caused by Treponema pallidum subspecies endemicum. This disease predominantly affects impoverished communities in arid regions, particularly among children, and is transmitted through direct contact with lesions or indirectly via shared utensils.​ Epidemiology and Transmission Bejel is endemic in the Sahel region of

Laryngeal edema

Laryngeal edema refers to the swelling of the laryngeal tissues, which can lead to significant airway obstruction and respiratory distress. This condition often arises as a complication following endotracheal intubation, particularly in critically ill patients. Understanding its causes, symptoms, and management strategies is crucial for effective treatment and prevention of associated complications. Causes of Laryngeal

Large Granular Lymphocytic (LGL) Leukemia

Large granular lymphocytic leukemia (LGL leukemia) is a rare hematologic malignancy characterized by an abnormal increase in large granular lymphocytes. It primarily affects T cells (T-LGL leukemia) or natural killer (NK) cells (NK-LGL leukemia) and often presents as a chronic condition with a slow progression. Types of Large Granular Lymphocytic Leukemia LGL leukemia is categorized

Langerhans Cell Histiocytosis (LCH)

Langerhans Cell Histiocytosis (LCH) is a rare disorder characterized by the abnormal proliferation of Langerhans cells, a type of dendritic cell involved in the immune response. These abnormal cells accumulate in various tissues, leading to damage and dysfunction. Causes and Risk Factors The exact cause of LCH remains unclear, but research suggests it may have

Lamivudine-Refractory Chronic Hepatitis B

Lamivudine, a nucleoside analog, has been a cornerstone in the treatment of chronic hepatitis B virus (HBV) infection. However, prolonged use has led to the emergence of lamivudine-resistant HBV strains, characterized by mutations in the viral polymerase gene, notably at positions rtL180M and rtM204V/I. These mutations diminish the drug’s efficacy, resulting in viral rebound and

Lamellar Ichthyosis

Lamellar Ichthyosis (LI) is a rare congenital skin disorder affecting keratinization. It is characterized by thick, plate-like scales covering the body from birth. This condition results from genetic mutations affecting the epidermis, leading to impaired skin barrier function. Causes and Genetic Basis Lamellar Ichthyosis is inherited in an autosomal recessive pattern, meaning both parents must

Lactose Intolerance

Lactose intolerance is the inability to digest lactose, a sugar found in milk and dairy products. This condition occurs due to a deficiency of lactase, the enzyme responsible for breaking down lactose in the small intestine. When undigested lactose reaches the colon, it ferments and causes digestive discomfort. Causes of Lactose Intolerance Lactose intolerance can

​Lactation

Lactation is the physiological process whereby the mammary glands produce and secrete milk, providing essential nutrition and immunological protection to infants. This intricate process involves a coordinated interplay of hormonal signals, anatomical structures, and maternal behaviors. Anatomy of the Mammary Glands The mammary glands, commonly referred to as breasts, are complex structures composed of glandular