HER2-Negative and CLDN18.2-Positive Gastric

Gastric and gastroesophageal junction (GEJ) adenocarcinomas are aggressive malignancies with limited treatment options. Recent advancements have identified CLDN18.2 as a promising biomarker in patients with HER2-negative tumors, offering new therapeutic possibilities. Understanding HER2-Negative Gastric Cancer HER2-negative gastric cancer refers to tumors that lack overexpression of the human epidermal growth factor receptor 2 (HER2) protein. These

HER2 Mutant Non-Small Cell Lung Cancer

Human Epidermal Growth Factor Receptor 2 (HER2) mutant non-small cell lung cancer (NSCLC) is a rare but significant subtype of lung cancer characterized by specific genetic alterations. These mutations drive cancer growth and present unique challenges in diagnosis and treatment. Understanding the molecular landscape of HER2 mutations is crucial for effective clinical management. Understanding HER2

Hepatorenal Syndrome: Causes, Symptoms, Diagnosis

Hepatorenal syndrome (HRS) is a severe complication of advanced liver disease characterized by functional kidney failure. This condition is commonly associated with cirrhosis, acute liver failure, or alcoholic hepatitis. HRS is a life-threatening disorder requiring immediate medical intervention. Types of Hepatorenal Syndrome Hepatorenal syndrome is classified into two types: Causes and Risk Factors The primary

Hepatitis B Vaccination: Essential Information

Hepatitis B is a serious liver infection caused by the hepatitis B virus (HBV). The most effective preventive measure against this disease is vaccination. The hepatitis B vaccine is safe, highly effective, and recommended for people of all ages. What is Hepatitis B? Hepatitis B is a viral infection that affects the liver, potentially leading

Hepatitis B Prevention: Effective Strategies for Protection

Hepatitis B is a serious liver infection caused by the hepatitis B virus (HBV). As a global health concern, it requires comprehensive preventive strategies to reduce transmission rates and safeguard public health. Understanding Hepatitis B Transmission Hepatitis B spreads primarily through contact with infectious body fluids. Common transmission routes include: Importance of Hepatitis B Prevention

Hepatitis A Vaccination: Everything You Need to Know

Hepatitis A is a contagious liver infection caused by the hepatitis A virus (HAV). It is commonly transmitted through contaminated food, water, or close contact with an infected individual. Vaccination is a highly effective preventive measure against this disease. Importance of Hepatitis A Vaccination The hepatitis A vaccine is crucial for preventing infection and its

Hepatic Veno-Occlusive Disease

Hepatic Veno-Occlusive Disease (VOD), also known as sinusoidal obstruction syndrome (SOS), is a rare but potentially life-threatening condition characterized by the blockage of small veins in the liver. It is often associated with stem cell transplantation, chemotherapy, and other liver-related complications. Causes and Risk Factors Primary Causes Risk Factors Symptoms of Hepatic Veno-Occlusive Disease Early

Hepatic Encephalopathy: Causes, Symptoms, Diagnosis

Hepatic encephalopathy (HE) is a complex neurological disorder resulting from liver dysfunction, primarily seen in patients with chronic liver disease or acute liver failure. This condition arises due to the accumulation of toxic substances in the bloodstream that the liver fails to adequately filter. HE can present in various forms, ranging from mild cognitive impairment

Hepatic Coma: Causes, Symptoms, Diagnosis, and Treatment

Hepatic coma, also known as stage 4 hepatic encephalopathy, is a severe and life-threatening condition resulting from liver failure. It occurs when toxins such as ammonia accumulate in the bloodstream, impairing brain function. This condition requires immediate medical intervention to prevent fatal outcomes. Causes of Hepatic Coma Several factors can trigger hepatic coma, including: Stages

Hepatic Cirrhosis: Causes, Symptoms, Diagnosis, and Treatment

Hepatic cirrhosis is a severe liver condition characterized by irreversible scarring (fibrosis) that impairs liver function. This chronic disease progressively damages the liver, affecting its ability to perform vital tasks such as detoxification, metabolism, and bile production. Causes of Hepatic Cirrhosis Several underlying conditions can contribute to hepatic cirrhosis, including: 1. Chronic Alcohol Abuse Excessive